In Vitro ADME and PK Support
Advancing a compound that has the right balance of properties into pre-clinical development is an important consideration for the success of any drug discovery program. In vitro ADME
(absorption, distribution, metabolism and excretion)
and pharmacokinetic testing can help to find those drug-like candidates. In addition to potency and selectivity, solubility, stability and permeability are important ADME factors that play an important role in determining a successful program outcome.
We understand the urgency in generating high quality data to advance your discovery programs in a timely manner and have established a core group of in vitro ADME and pharmacokinetic services to meet these needs. Our staff is dedicated to a highly interactive and collaborative relationship with our clients to assure that the individual needs of your program and the correctly customized tests are appropriately addressed.
Our modern laboratory includes ABI 4000 and ABI 4000 Q Trap™ LC-MS/MS systems that have the highest sensitivity for low level quantification.