Pre-Formulation
Formulation Development
Real-time and Accelerated Stability Testing
Container-closure Selection and Compatibility Studies
Dose Recovery

 

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CASE STUDY 1
Parenteral dosage form development of a highly insoluble molecule
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CASE STUDY 2
Salt form optimization and lyophilized parenteral formulation development
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CASE STUDY 3
Oral liquid formulation development
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CASE STUDY 4
Accelerated stability studies to support a screening IND
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CASE STUDY 5
Lead Optimization: Solubility and formulation screen for efficacy and PK studies

 

Formulation Development

Wolfe Laboratories, Inc. has a wide range of experience in pre-clinical formulation development for small molecules, proteins and peptides as solutions and dispersed systems (suspensions, emulsions, liposomes). Preclinical formulation development is often a challenging field for molecules possessing poor aqueous solubility, and WLI has the ability to conduct small scale testing to meet specific project needs. Additionally, sterile handling and formulation in aseptic enclosure is routinely conducted at Wolfe Laboratories, Inc.

    • Pre-Formulation
    • Formulation Development
    • Real-time and Accelerated Stability Testing
    • Container-closure Selection and Compatibility Studies
    • Dose Recovery

 

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