Pre-Formulation
Formulation Development
Real-time and Accelerated Stability Testing
Container-closure Selection and Compatibility Studies
Dose Recovery

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CASE STUDY 1
Parenteral dosage form development of a highly insoluble molecule
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CASE STUDY 2
Salt form optimization and lyophilized parenteral formulation development
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CASE STUDY 3
Oral liquid formulation development
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CASE STUDY 4
Accelerated stability studies to support a screening IND
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CASE STUDY 5
Lead Optimization: Solubility and formulation screen for efficacy and PK studies

Formulation

Formulation is the development of a customized dosage form for a specific administration route.  WLI has accumulated years of experience in development of vehicles for administration of pharmaceuticals.  Formulation studies are designed and performed with attention to every detail from use of excipients that are generally recognized as safe (GRAS), to identification of potential stability problems, to composition of clear and precise compounding instructions.

The types of formulation development studies conducted by WLI vary and reflect the range of administration routes employed in clinical practice.  Most of our work focuses on oral and intravenous routes of administration.  We do work with clients interested in topical, ophthalmic, and subcutaneous pharmaceuticals.  Moreover, we welcome projects that involve specialty dosage forms and proprietary administration devices, and we have experience with such studies.

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