Wolfe Laboratories - From Concept to Creation with Confidence

Analytical Method Development
Protein Characterization
Solid-State Characterization
Stability-Indicating Analytical Methods
Identification of Impurities and Degradation Products
Additional Analytical Applications

>	CASE STUDY 1 Parenteral dosage form development of a highly insoluble molecule
>	CASE STUDY 2 Salt form optimization and lyophilized parenteral formulation development
>	CASE STUDY 3 Oral liquid formulation development
>	CASE STUDY 4 Accelerated stability studies to support a screening IND
>	CASE STUDY 5 Lead Optimization: Solubility and formulation screen for efficacy and PK studies

Solid state characterization

Solid state properties of an active pharmaceutical ingredient (API) may influence its performance in several disparate contexts, from oral bioavailability to storage stability to ease of processing. In addition, investigation of solid state properties of an API may be beneficial for patent protection purposes.

WLI offers a suite of analytical services for characterization of solids. Frequently, several complimentary techniques are used to determine solid state properties of an analyte. However, assays based on each analytical technique are available on a fee-per-sample basis.